1) Radjabzadeh, D., Bosch, J.A., Uitterlinden, A.G. et al. Gut microbiome-wide association study of depressive symptoms. Nat Commun 13, 7128, 2022.
2) Steenbergen, L., Sellaro, R., Van Hemert, S., et al. A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood, Brain, Behavior, and Immunity, Volume 48, 2015, Pages 258-264, ISSN 0889-1591.
3) Sanada K, Nakajima S, Kurokawa S, et al. Gut microbiota and major depressive disorder: A systematic review and meta-analysis.J Affect Disord. 2020 Apr 1;266:1-13. Epub 2020 Jan 23. PMID: 32056863.
4) Mayer, E.A., Nance, K., Chen, S., The Gut-Brain Axis. Annu Rev Med. 2022 Jan 27;73:439-453. Epub 2021 Oct 20. PMID: 34669431.
5) Messaoudi, M., Violle, N., Bisson, J.F., et al. Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers, Gut Microbes, 2:4, 256-261, 2011.
6) Kato-Kataoka, A., Nishida, K., Takada, M., et al.Fermented milk containing Lactobacillus casei strain Shirota prevents the onset of physical symptoms in medical students under academic examination stress. Benef Microbes. 2016;7(2):153-6. Epub 2015 Dec 21. PMID: 26689231.
7) Salleh, R.M., Kuan, G., Aziz, M.N.A., et al. Effects of Probiotics on Anxiety, Stress, Mood and Fitness of Badminton Players. Nutrients. 2021 May 24;13(6):1783. PMID: 34073684; PMCID: PMC8225117.
8) Mörkl, S., Butler, M.I., Holl, A., Probiotics and the Microbiota-Gut-Brain Axis: Focus on Psychiatry. Curr Nutr Rep. 2020 Sep;9(3):171-182. Erratum in: Curr Nutr Rep. 2020 Jun 5; PMID: 32406013; PMCID: PMC7398953.
9) Otaka M, Kikuchi-Hayakawa H, Ogura J, et al., Effect of Lacticaseibacillus paracasei Strain Shirota on Improvement in Depressive Symptoms, and Its Association with Abundance of Actinobacteria in Gut Microbiota. Microorganisms. 2021 May 10;9(5):1026. PMID: 34068832.
Literatuur
Op deze pagina vind je de wetenschappelijke onderbouwing van onze materialen en webinars. Op zoek naar een specifieke bron? Mail ons.
1) McFarland LV. Epidemiology, risk factors and treatments for antibiotic-associated diarrhea. Dig Dis. 1998 Sep-Oct;16(5):292-307
2) Agamennone et al. BMC A practical guide for probiotics applied to the case of antibiotic-associated diarrhea in The Netherlands, Gastroenterology. 2018; 18:103.
3) McFarland LV. Emerging therapies for Clostridium difficile infections. Expert Opin Emerging Drugs; 2011. 16 (3): 425-439.
4) Claassen E. Cost-benefi t relation of diet and probiotics in iatrogenic bowel irregularity (IBI). Frontiers in Pharmacology. 2014;5:14.
5) Videlock E.J., Cremonini F. Meta-analysis: probiotics in antibiotic-associated diarrhoea. Aliment Pharmacol Ther. 2012; 35: 1355-1369.
6) Hempel, S. et al. Probiotics for the Prevention and Treatment of Antibiotic-Associated Diarrhea, A Systematic Review and Meta-analysis. JAMA. 2012;307(18):1959-1969.
7) Goldenberg JZ. et al. Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database Syst Rev. 2017;12(12):CD006095.
8) Szajewska H. et al. Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Children. J Pediatr Gastroenterol Nutr. 2016;62(3):495-506.
9) Wong S. et al. Lactobacillus casei Shirota probiotic drink reduces antibiotic-associated diarrhoea in patients with spinal cord injuries: a randomised controlled trial. Br J Nutr. 2014 ; 111 (4): 672-8
10) Pirker A. et al. Effects of antibiotic therapy on the gastrointestinal microbiota and the infl uence of Lactobacillus casei. Food and Agricultural Immunology 2013;24(3):315-330
11) Stockenhuber, A. et al. Preventing Antibiotic Associated Diarrhoea using a Probiotic Lactobacillus casei Preparation. Gut 2008; 57 (Suppl II) A20
12) Lee L. et al. Prevention of relapse following Clostridium difficile infection using probiotic Lactobacillus casei Shirota. International Journal of Probiotics & Prebiotics. 2013; 8(4):145-148.
13) Flach J, et al. The underexposed role of food matrices in probiotic products: Reviewing the relationship between carrier matrices and product parameters. Crit Rev Food Sci Nutr. 2018;58(15):2570-2584.
14) Ouwehand A. et al. Effectiveness of Multi-strain Versus Single-strain Probiotics: Current Status and Recommendations for the Future, J Clin Gastroenterol. 52():S35–S40, NOV 2018
15) Lee B. et al Attenuation of colitis by Lactobacillus casei BL23 is dependent on the dairy delivery matrix. Appl Environ Microbiol. 2015;81(18):6425-35.
16) Burgain J. Encapsulation of Lactobacillus rhamnosus GG in microparticles: Influence of casein to whey protein ratio on bacterial survival during digestion. Innovative Food Science & Emerging Technologies. 2013. 19: 233–242
17) Agamennone V. et al. Een praktische gids voor probiotica ter preventie van antibiotica-gerelateerde diarree in Nederland. Nederlands Platform voor Farmaceutisch Onderzoek. 2019;4:a1689
18) Guo Q, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database of Systematic Rev. 2019; 4(4): CD004827.
19) Former, M. Probiotica als aanvullende therapie bij antibioticum geassocieerde diarree, Voeding en Visie, 2001. 24. 2: 6-7.
20) Hickson M. et al. Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial. BMJ 2007 ;335(7610):80
21) ISAPP Probiotic Guide
1) Claesson M.J. et al. Gut microbiota composition correlates with diet and health in the elderly. Nature. 2012 Aug 9;488(7410):178-84.
2) Eldermet-project, University College Cork, Cork University Hospital, and Teagasc, Moorepark
3) Ragonnaud, E., Biragyn, A. Gut microbiota as the key controllers of “healthy” aging of elderly people. Immun Ageing. 2021;18:2.
4) Roswall J, et al. Developmental trajectory of the healthy human gut microbiota during the first 5 years of life. Cell Host Microbe. 2021 May 12;29(5):765-776.
5) Duncan S.H., Flint H.J. Probiotics and prebiotics and health in ageing populations. Maturitas. 2013 May;75(1):44-50.
6) Tiihonen, K. et al. Human intestinal microbiota and healthy ageing. Ageing Res Rev. 2010 Apr; 9(2):107-16.
7) Berg, S. van den, et al. Voeding in relatie tot aandoeningen en medicijngebruik bij ouderen. Rijksinstituut voor Volksgezondheid en Milieu. 2012; RIVM Rapport 350047001.
8) Cevenini, E. et al. Inflamm-ageing. Curr Opin Clin Nutr Metab Care. 2013 Jan;16(1):14-20.
9) Bouterse, M. et al. Huisartsenzorg in cijfers, Obstipatie, Huisarts en Wetenschap. 2010; 9:463-463
10) Flach, J. et al. Economic Potential of Probiotic Supplementation in Institutionalized Elderly with Chronic Constipation. PharmaNutrition. 2018. 6. 10.1016
1. Berg, S. van den, et al. Voeding in relatie tot aandoeningen en medicijngebruik bij ouderen. Rijksinstituut voor Volksgezondheid en Milieu. 2012; RIVM Rapport 350047001.
2. Bouterse, M. et al. Huisartsenzorg in cijfers, Obstipatie, Huisarts en Wetenschap. 2010; 9:463-463
3. Claesson M.J. et al. Gut microbiota composition correlates with diet and health in the elderly. Nature. 2012 Aug 9; 488(7410):178-84
4. Flach, J. et al. Economic Potential of Probiotic Supplementation in Institutionalized Elderly with Chronic Constipation. PharmaNutrition. 2018. 6. 10.1016
5. Duncan S.H., Flint H.J. Probiotics and prebiotics and health in ageing populations. Maturitas. 2013 May;75(1):44-50.
6.Ocke M. et al. Diet of community-dwelling older adults : Dutch National Food Consumption Survey Older adults 2010-2012. Rijksinstituut voor Volksgezondheid en Milieu. RIVM Rapport 050413001.
7. Chmielewska, A., Szajewska, H. Systematic review of randomised controlled trials: Probiotics for functional constipation, World J Gastroenterol, 2010, January 7; 16(1): 69–75
8. Nieuwboer, M. van den, et al. Improving the bowel habits of elderly residents in a nursing home using probiotic fermented milk. Beneficial Microbes. 2015; Feb 17:1-8.
9. Frazzitta, Giuseppe et al. Severe Constipation in Parkinson’s Disease and in Parkinsonisms: Prevalence and Affecting Factors. Frontiers in neurology vol. 10 621. 18 Jun. 2019
10. Cassani, E. et al. Use of probiotics for the treatment of constipation in Parkinson’s disease patients. Minerva Gastroenterol Dietol. 2011; Jun;57(2):117-21.
11. Tan, A.H. et al. Probiotics for Parkinson’s disease: Current evidence and future directions. JGH Open, (2021) 5: 414-419.
12. Gras-Miralles, B., Cremonini, F. A critical appraisal of lubiprostone in the treatment of chronic constipation in the elderly, Clin Interv Aging. 2013; 8: 191–200.
13. Gandell D. et al. Treatment of constipation in older people. CMAJ. 2013 May 14;185(8):663-70.
14. Diemel, J.M. et al. NHG – Standaard Obstipatie, Huisarts en Wetenschap, 2010;53(9):484-98
15. Gezondheidsraad. Richtlijn voor de vezelconsumptie. Den Haag: Gezondheidsraad, 2006; publicatie nr 2006/03.
16. Ho, K.S. et al. Stopping or reducing dietary fiber intake reduces constipation and its associated symptoms, World J Gastroenterol, 2012 September 7; 18(33): 4593-4596
17. Kenny, K. A., Skelly, J.M. Dietary fiber for constipation in older adults: a systematic review. Clinical Effectiveness in Nursing, 2001; 5: 120-128
18. Fosnes GS, Lydersen S, Farup PG. Effectiveness of laxatives in elderly–a cross sectional study in nursing homes. BMC Geriatr. 2011 Nov 17;11:76.
19. Lenoir-Wijnkoop I, et al. Probiotics Reduce Health Care Cost and Societal Impact of Flu-Like Respiratory Tract Infections in the USA: An Economic Modeling Study. Front Pharmacol. 2019 Aug 28;10:980
20. Goldenberg JZ. et al. Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database Syst Rev. 2017;12(12):CD006095.
21. Videlock, E.J., Cremonini, F. Meta-analysis: probiotics in antibiotic-associated diarrhoea. Aliment Pharmacol Ther. 2012 Jun; 35(12):1355-69.
22. McFarland L. Emerging therapies for Clostridium difficile infections. Expert Opin Emerg Drugs. 2011 Sep;16(3):425-39.
23. Hempel S. et al. Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis. JAMA. 2012 May 9;307(18):1959-69.
24. Hickson M. et al. Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial.BMJ 2007;335:80.
25. Stockenhuber, A. et al. Preventing Antibiotic Associated Diarrhoea using a Probiotic Lactobacillus casei Preparation. Gut 2008; 57 (Suppl II) A20
26. Pirker, A. et al. Effects of antibiotic therapy on the gastrointestinal microbiota and the influence of Lactobacillus casei. Food and Agricultural Immunology, 2013; 24(3):315-330.
27. Lee L. et al. Prevention of relapse following Clostridium difficile infection using probiotic Lactobacillus casei Shirota. International Journal of Probiotics & Prebiotics. 2013; 8(4):145-148.
1. Bermingham, K., Linenberg, I., Hall, W., et al. (2022). Menopause is associated with postprandial metabolism, metabolic health, and lifestyle: the ZOE PREDICT study. EBioMedicine, 85, 104303.
2. Peters, B. A., Santoro, N., Kaplan, R. C., et al. (2022). Spotlight on the gut microbiome in Menopause: Current insights. International Journal of Women’s Health, Volume 14, 1059–1072.
3. Shieh, A., Epeldegui, M., Karlamangla, A. S., et al. (2020). Gut permeability, inflammation, and bone density across the menopause transition. JCI insight, 5(2).
4. Radjabzadeh, D., Bosch, J. A., Uitterlinden, A. G., et al. (2022). Gut Microbiome-wide Association Study of depressive Symptoms. Nature Communications, 13(1).
5. Sanada, K., Nakajima, S., Kurokawa, S., et al. (2020). Gut Microbiota and Major Depressive Disorder: A Systematic Review and Meta-analysis. Journal of Affective Disorders, 266, 1–13.
6. Steenbergen, L., Sellaro, R., Van Hemert, S., et al. (2015). A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to SAD mood. Brain Behavior and Immunity, 48, 258–264.
7. Messaoudi, M., Violle, N., Bisson, J., et al. (2011). Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticusR0052 andBifidobacterium longumR0175) in healthy human volunteers. Gut microbes, 2(4), 256–261.
8. Kato-Kataoka, A., Nishida, K., Takada, M., et al. (2016). Fermented milk containing Lactobacillus casei strain shirota prevents the onset of physical symptoms in medical students under academic examination stress. Beneficial Microbes, 7(2), 153–156.
9. Morita, E., Yokoyama, H., Imai, D., et al. (2019). Aerobic exercise training with brisk walking increases intestinal bacteroides in healthy elderly women. Nutrients, 11(4), 868.
10. Strasser, B., Wolters, M., Weyh, C., et al. (2021). The effects of lifestyle and diet on gut microbiota composition, inflammation and muscle performance in our aging society. Nutrients, 13(6), 2045.
11. Gezondheidsraad (2017). Beweegrichtlijnen 2017. Den Haag: Gezondheidsraad, 2017; publicatienr. 2017/08.
12. Cicchinelli, S., Rosa, F., Manca, F., et al. (2023b). The Impact of smoking on Microbiota: A Narrative review. Biomedicines, 11(4), 1144.
13. Bai, X., Wei, H., Liu, W., et al. (2022b). Cigarette smoke promotes colorectal cancer through modulation of gut microbiota and related metabolites. Gut, 71(12), 2439–2450.
14. Zhu, D., Chung, H., Pandeya, N., et al. (2018). Relationships between intensity, duration, cumulative dose, and timing of smoking with age at menopause: A pooled analysis of individual data from 17 observational studies. PLOS Medicine, 15(11), e1002704.
15. Dotlic, J., Marković, N., Gazibara, T. (2021). Patterns of smoking and menopause-specific quality of life: smoking duration matters more. Behavioral Medicine, 49(1), 29–39.
16. Overgangsklachten (Folder). (2021, 5 augustus). Catharina Ziekenhuis. https://www.catharinaziekenhuis.nl/patientenfolders/overgangsklachten-gyn-039/
17. Trimbos-instituut. (2022). Alcohol en de overgang. https://www.trimbos.nl/kennis/alcohol/alcohol-en-vrouwen/alcohol-en-de-overgang/
18. Engen, P.A., Green, S.J., Voigt, R.M., et al. (2015). The Gastrointestinal Microbiome: Alcohol Effects on the Composition of Intestinal Microbiota. Alcohol research : current reviews, 37(2), 223–236.
19. Rostami-Moez, M., Shobeiri, F., Otogara, M., et al. (2023). Examining the Health-Related Needs of Females During Menopause: A Systematic Review study. Journal of Menopausal Medicine, 29(1), 1.
20. Malan-Müller, S., Valles-Colomer, M., Raes, J., et al. (2018). The Gut Microbiome and Mental Health: Implications for Anxiety- and Trauma-Related Disorders. Omics A Journal of Integrative Biology, 22(2), 90–107.
21. Pluchino, N., Bucci, F., Cela, V., et al. (2011). Menopause and Mental Well-Being: Timing of symptoms and Timing of hormone treatment. Women’s Health, 7(1), 71–80.
22. Tandon, V. R., Sharma, S., Mahajan, A., et al. (2022). Menopause and sleep disorders. Journal of Mid-life Health, 13(1), 26.
23. Shafie, M., Rad, A. H., Mohammad-Alizadeh-Charandabi, S., et al. (2023). The effect of probiotics on mood and sleep quality in postmenopausal women: A triple-blind randomized controlled trial. Clinical Nutrition ESPEN, 56, 15–23.
24. Reynolds, A., Paterson, J.L., Ferguson, S.A., et al. (2017). The Shift Work and Health Research agenda: considering changes in gut microbiota as a pathway linking shift work, sleep loss and circadian misalignment, and metabolic disease. Sleep Medicine Reviews, 34, 3–9.
25. Thuisarts.nl. (2022). Ik ben in de overgang en heb opvliegers. https://www.thuisarts.nl/overgang/ik-ben-in-overgang-en-heb-opvliegers
26. Barnard, N.D., Kahleova, H., Holtz, D., et al. (2022). A Dietary Intervention for Vasomotor Symptoms of Menopause: a randomized, controlled trial. Menopause, 30(1), 80–87.
27. Barnard, N.D., Kahleova, H., Holtz, D., et al. (2021). The Women’s Study for the Alleviation of Vasomotor Symptoms (WAVS): a randomized, controlled trial of a plant-based diet and whole soybeans for postmenopausal women. Menopause, 28(10), 1150–1156.
28. Scavello, I., Maseroli, E., Di Stasi, V., et al. (2019). Sexual health in menopause. Medicina-lithuania, 55(9), 559.
29. Del Carmen Carcelén-Fraile, M., Aibar-Almazán, A., Martínez-Amat, A., et al. (2020). Effects of physical exercise on sexual function and quality of sexual life related to menopausal Symptoms in peri- and postmenopausal women: a systematic review. International Journal of Environmental Research and Public Health, 17(8), 2680.
30. Nicolosi, A., Laumann, E.O., Glasser, D.B., et al. (2004). Global Study of Sexual Attitudes and Behaviors Investigators’ Group. Sexual behavior and sexual dysfunctions after age 40: the global study of sexual attitudes and behaviors. Urology. Nov;64(5):991-7.
31. Verheul-Koot, M. A., Torremans-Weijgertse, T. G. (2023) Voeding in de overgang; Gezond de overgang door met voedings- en leefstijladviezen in de preventie en behandeling van overgangsklachten. VoedingOnline.
32. Lecerf, L.M. (2021). Conseils nutritionnels pour la femme ménopausée. RPC les femmes ménopausées du CNGOF et du GEMVI. Gynécologie Obstétrique Fertilité & Sénologie, 49(5), 349–357.
33. Da Silva, T. R., Oppermann, K., Reis, F. M., et al. (2021c). Nutrition in Menopausal Women: A Narrative review. Nutrients, 13(7), 2149.
34. Gezondheidsraad (2015). Richtlijnen goede voeding 2015. Den Haag: Gezondheidsraad 2015; publicatienr. 2015/24
35. Nederlands Huisartsen Genootschap (2022). De overgang. NHG-Richtlijnen. https://richtlijnen.nhg.org/standaarden/de-overgang
36. Oude Hengel, K., In der Maur, M., De Wolff, M., et al. (2022). De overgang: klachten en de invloed op het werk, TNO 2022 R10823. p.6
37. Singh, P. (2013). Andropause: current concepts. Indian Journal of Endocrinology and Metabolism, 17(9), 621.
38. Huhtaniemi, I.T. (2014). Andropause – Lessons from the European Male Ageing Study. Annales D Endocrinologie, 75(2), 128–131.
39. Nieuwdorp, M. (2022). Wij zijn onze hormonen., Uitgeverij De Bezige Bij b.v.
1) Diemel, J.M. et al. NHG – Standaard Obstipatie, Huisarts en Wetenschap. 2010;53(9):484-98
2) Bouterse, M. et al. Huisartsenzorg in cijfers, Obstipatie, Huisarts en Wetenschap. 2010;9:463-463.
3) Shafe, A.C.E. et al. The LUCK study: Laxative Usage in patients with GP diagnosed Constipation in the UK, within the general population and in pregnancy. An epidemiological study using the General Practice Research Database (GPRD) Therap Adv Gastroenterol. 2011. 4(6): 343–363.
4) Milliano, I. de, et al. Is a multispecies probiotic mixture effective in constipation during pregnancy? ‘A pilot study’, Nutr J. 2012, 11:80
5) Bosshard, W. et al. The treatment of chronic constipation in elderly people: an update. Drugs Aging. 2004, 21(14):911-30
6) Gras-Miralles, B., Cremonini, F. A critical appraisal of lubiprostone in the treatment of chronic constipation in the elderly, Clin Interv Aging. 2013; 8: 191–200
7) Flach J., Koks M., van der Waal M.B., Claassen E., Larsen O.F.A. Economic potential of probiotic supplementation in institutionalized elderly with chronic constipation (2018) PharmaNutrition, 6 (4) , pp. 198-206.
8) Rome Foundation, Appendix A, Rome III Diagnostic Criteria for Functional Gastrointestinal Disorders
9) Kumar, P., Clark, M. (eds.) Clinical Medicine. 2012 8th ed. Edinburgh: Elsevier Saunders
10) Chmielewska, A., Szajewska, H. Systematic review of randomised controlled trials: Probiotics for functional constipation, World J Gastroenterol. 2010; 16(1): 69–75
11) Gezondheidsraad. Richtlijn voor de vezelconsumptie. Den Haag: Gezondheidsraad, 2006; publicatie nr 2006/03. ISBN 90-5549-589-1
12) Ho, K.S. et al. Stopping or reducing dietary fiber intake reduces constipation and its associated symptoms, World J Gastroenterol, 2012; 7; 18(33): 4593-4596
13) Kenny, K. A., Skelly, J.M. Dietary fiber for constipation in older adults: a systematic review. Clin. Eff Nurs. 2001;5:120-128
14) Fosnes, G.S. et al. Effectiveness of laxatives in elderly – a cross sectional study in nursing homes. BMC Geriatr. 2011;11.76
15) Horst, H.E. van der, et al. NHG-Standaard Prikkelbaredarmsyndroom (PDS) (Eerste herziening) Huisarts en Wetenschap. 2012; 55(5):204-9
16) Koebnick, C. et al. Probiotic beverage containing Lactobacillus casei Shirota improves gastrointestinal symtoms in patients with chronic constipation. Can J Gastroenterol. 2003; 17(11):655-9.
17) Yang Y.X. et al. Effect of a fermented milk containing Bifidobacterium lactis DN-173101 on Chinese constipated women. World J. Gastroenterol. 2008; 14: 6237-6243
18) Mollenbrink, M., Bruckschen, E. Treatment of chronic constipation with physiologic Escherichia coli bacteria. Results of a clinical study of the effectiveness and tolerance of microbiological therapy with the E. coli Nissle 1917 strain (Mutaflor). Med Klin, 1994 (Munich) 89: 587–593
19) Ouwehand AC. et al. Effectiveness of Multi-strain Versus Single-strain Probiotics: Current Status and Recommendations for the Future, J Clin Gastroenterol. 2018; 52(suppl 1):S35–S40.
20) Lee B. et al. Attenuation of colitis by Lactobacillus casei BL23 is dependent on the dairy delivery matrix. Appl Environ Microbiol. 2015;81(18):6425-6435
21) Burgain J. Encapsulation of Lactobacillus rhamnosus GG in microparticles: Influence of casein to whey protein ratio on bacterial survival during digestion. Innovative Food Science & Emerging Technologies. 2013;(19): 233–242
22) Flach et al. The underexposed role of food matrices in probiotic products: Reviewing the relationship between carrier matrices and product parameters. Crit Rev Food Sci Nutr. 2018;58(15):2570-2584.
23) Ouwehand AC. A review of dose-responses of probiotics in human studies. Benef ical Microbes. 2017;8(2):143-151.
24) ISAPP resources ‘What are probiotics?’
1. How mud boosts your immune system Alessia Franco and David Robson – BBC / Family Tree – 11th October 2022 https://www.bbc.com/future/article/20220929-how-outdoor-play-boosts-kids-immune-systems
2. Prebiotics in the Infant Microbiome: The Past, Present, and Future Miqdady M, Al Mistarihi J, Azaz A, Rawat D.. Pediatr Gastroenterol Hepatol Nutr. 2020 Jan;23(1):1-14 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966216
3. Probiotics in Pediatrics. A Review and Practical Guide Depoorter L, Vandenplas Y.. Nutrients. 2021 Jun 24;13(7):2176. doi: 10.3390/nu13072176. PMID: 34202742; PMCID:PMC8308463. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308463/
4. Efficacy of probiotics on digestive disorders and acute respiratory infections: a controlled clinical trial in young Vietnamese children Mai, T.T., Thi Thu, P., Thi Hang, H. et al.. Eur J Clin Nutr 75, 513–520 (2021) https://www.nature.com/articles/s41430-020-00754-9
5. Role of probiotic in preventing acute diarrhoea in children: a community-based, randomized, double-blind placebo-controlled field trial in an urban slum Sur D, et al. Epidemiol Infect. 2011 Jun;139(6):919-26.doi:10.1017/ S0950268810001780. Epub 2010 Jul 30. PMID: 20670468. https://pubmed.ncbi.nlm.nih.gov/20670468/
6. Probiotics for the prevention of pediatric antibiotic associated diarrhea Qin Guo, Joshua Z Goldenberg, Claire Humphrey, Regina El Dib, Bradley C Johnston https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD004827.pub5/full
7. Probiotic and synbiotic safety in infants under two years of age van den Nieuwboer M, Claassen E, Morelli L, Guarner F, Brummer RJ.. Benef Microbes. 2014 Mar;5(1):45-60. https://pubmed.ncbi.nlm.nih.gov/24463207/
8. Safety of probiotics and synbiotics in children under 18 years of age. van den Nieuwboer M, Brummer RJ, Guarner F, Morelli L, Cabana M, Claassen E. Benef Microbes. 2015;6(5):615-30. https://pubmed.ncbi.nlm.nih.gov/25809217/
9. Fermented Foods as a Dietary Source of Live Organisms.Rezac S, Kok CR, Heermann M, Hutkins R. Front Microbiol. 2018 Aug 24;9:1785 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117398/
1. Pot GK, Voshol PJ, Kaldenberg E, van Eekelen A. Je bent niet alleen wat je eet, maar ook wanneer je eet. Ned Tijdschr voor Voeding en Diet. 2021 Juni
2. Gezondheidsraad. Gezondheidsrisico’s door nachtwerk. Den Haag; 2017. Available from: https://www.gezondheidsraad.nl/binaries/gezondheidsraad/documenten/adviezen/2017/10/24/gezondheidsrisicos-door-nachtwerk/achtergronddocument-Gezondheidsrisico%27s-door-nachtwerk.pdf
3. Oike H, Oishi K, Kobori M. Nutrients, Clock Genes, and Chrononutrition. Curr Nutr Rep. 2014 Jan;3(3):204–12.
4. Tahara Y, Shibata S. Chronobiology and nutrition. Neuroscience. 2013 Dec 3;253(3):78–88.
5. Voigt RM, Forsyth CB, Green SJ, Mutlu E, Engen P, Vitaterna MH, et al. Circadian disorganization alters intestinal microbiota. PLoS One. 2014;9(5):e97500.
6. Liang X, FitzGerald GA. Timing the Microbes: The Circadian Rhythm of the Gut Microbiome: Journal of Biological Rhythms. 2017 Sep 1;32(6):505-515.
7. Pot GK, Hardy R, Stephen AM. Irregular consumption of energy intake in meals is associated with a higher cardio-metabolic risk in adults of a British birth cohort. Int J Obes. 2014;38(12):1518–24.
8. Pot GK, Hardy R, Stephen AM. Irregularity of energy intake at meals: prospective associations with the metabolic syndrome in adults of the 1946 British birth cohort. Br J Nutr. 2016;115(2):315–23.
9. Bandín C, Martinez-Nicolas A, Ordovás JM, Madrid JA, Garaulet M. Circadian rhythmicity as a predictor of weight-loss effectiveness. Int J Obes. 2014 Aug 15 ;38(8):1083–8.
10. Schoenfeld BJ, Aragon AA, Krieger JW. Effects of meal frequency on weight loss and body composition: a meta-analysis. Nutr Rev. 2015 Mar 1;73(2):69-82.
11. Moon S, Kang J, Kim SH, Chung HS, Kim YJ, Yu JM, et al. Beneficial effects of time-restricted eating on metabolic diseases: A systemic review and meta- analysis. Vol. 12, Nutrients. MDPI AG; 2020. p. 1267.
12. Muñoz JSG, Gomez Gallego M, Diaz Soler I, Ortega MCB, Martinez Caceres CM, Morante JJH. Effect of a chrono-type-adjusted diet on weight loss effectiveness: A randomized clinical trial. Clin Nutr 2020 Apr;39(4):1041-1048.
13. Al Khatib HK, Harding SV, Darzi J, Pot GK. The effects of partial sleep deprivation on energy balance: a systematic review and meta-analysis. Eur J Clin Nutr. 2017;71(5):614–24.
14. NED TIJDSCHR GENEESKD. 2015;159: A9601:Available from: Tijd van slapen | NTvG
1) Sakai T, et al. (2011) Int. J. Food Sci Nutr 62(4): 423-30.
2) Matsumoto K, et al. (2006). Biosci Microflora 25(2): 39-48.
3) Nieuwboer van den M, et al. (2015) Benef Microbes, 6(4): 397-403.
4) Koebnick C, et al. (2003) Can J Gastroenterol; 17 (11):655-659.
5) Krammer HJ, et al. (2011) Coloproctology, Volume 33, Number 2, p.109-113.
6) Sugita T, et al. (1994) Jpn J Pediatr, 47, 2755-2762.
7) Matsumoto K, et al. (2010) J Biosci Bioeng, 110(5):547-52.
8) Sur D, et al. (2010) Epidem Inf, 139(6):919-26.
9) Pirker A, et al. (2013) Food and Agric Immunol 24(3):315-330.
10) Wong S, et al. (2014) Br J Nutr. Feb;111(4): 672-8.
11) Thijssen AY, et al. (2016) Eur J Gastroenterol Hepatol. Jan;28(1):8-14.
12) Barret JS, et al. (2008) World J Gastroenterol 14(32): 5020-5024.
13) Gleeson M, et al. (2011) Int. J Sport Nutr Exer Metabol 21: 55-64.
14) Cats A, et al. (2003) Aliment Pharmacol Ther, 17 (3):429-435.
15) Ouwehand AC. (2017) Benefical Microbes 8(2):143-151.
16) Hoveyda N, et al. (2009) BMCGastroenterol; 16 (9):1
1)Marco, M. L., Sanders, M. E., Gänzle, M. G., Arrieta, M. C., Cotter, P. D., De Vuyst, L., Hill, C.,Holzapfel, W. H., Lebeer, S., Merenstein, D., Reid, G., Wolfe, B. E., & Hutkins, R. W. (2021). The International Scientific Association for Probiotics and Prebiotics (ISAPP) Consensus Statement on Fermented Foods. Nature Reviews Gastroenterology & Hepatology, 18(3), 196–208.
2)Hill, C., Guarner, F., Reid, G., Gibson, G. R., Merenstein, D., Pot, B., Morelli, L., Canani, R. B., Flint,H. J., Salminen, S., Calder, P. C., & Sanders, M. E. (2014). The International Scientific Association for Probiotics and Prebiotics Consensus Statement on the scope and appropriate use of the termProbiotic. Nature Reviews Gastroenterology & Hepatology, 11(8), 506–514.
3)Rezac, S. D., Kok, C. R., Heermann, M., & Hutkins, R. W. (2018). Fermented foods as a dietary source of live organisms. Frontiers in Microbiology, 9.
4)International Scientific Association for Probiotics and Prebiotics. (2021, 10 september). Probiotics vs fermented foods infographic – International Scientific Association for Probiotics and Prebiotics (ISAPP). International Scientific Association for Probiotics and Prebiotics (ISAPP).https://isappscience.org/probiotics-vs-fermented-foods-infographic/
5)International Scientific Association for Probiotics and Prebiotics. (2020). Do all fermented foods contain a probiotic? – International Scientific Association for Probiotics and Prebiotics. International Scientific Association for Probiotics and Prebiotics (ISAPP).
6)Voedingscentrum. (z.d.). Fermentatie. https://www.voedingscentrum.nl/encyclopedie/fermentatie.asp
- Bäckhed F, et al. Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life. Cell Host Microbe. 2015 May 13;17(5):690-703. doi: 10.1016/j.chom.2015.04.004. Erratum in: Cell Host Microbe. 2015 Jun 10;17(6):852. Jun, Wang [corrected to Wang, Jun]. Erratum in: Cell Host Microbe. 2015 Jun 10;17(6):852. doi: 10.1016/j.chom.2015.05.012. PMID: 25974306.
- Koenig JE, et al. Succession of microbial consortia in the developing infant gut microbiome. Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1(Suppl 1):4578-85. doi: 10.1073/pnas.1000081107. Epub 2010 Jul 28. PMID: 20668239; PMCID: PMC3063592.
- Yatsunenko, T. et al. Human gut microbiome viewed across age and geography. Nature, 2012. 486(7402), 222–227, https://doi.org/10.1038/nature11053
- Mady EA, et al. Impact of the mother’s gut microbiota on infant microbiome and brain development. Neurosci Biobehav Rev. 2023 Jul;150:105195. doi: 10.1016/j.neubiorev.2023.105195. Epub 2023 Apr 24. PMID: 37100161.
- Ragonnaud E, Biragyn A. Gut microbiota as the key controllers of “healthy” aging of elderly people. Immun Ageing. 2021 Jan 5;18(1):2. doi: 10.1186/s12979-020-00213-w. PMID: 33397404; PMCID: PMC7784378.
- Roswall J, et al. Developmental trajectory of the healthy human gut microbiota during the first 5 years of life. Cell Host Microbe. 2021 May 12;29(5):765-776.e3. doi: 10.1016/j.chom.2021.02.021. Epub 2021 Mar 31. PMID: 33794185.
- Kates AE, et al. Household Pet Ownership and the Microbial Diversity of the Human Gut Microbiota. Front Cell Infect Microbiol. 2020 Feb 28;10:73. doi: 10.3389/fcimb.2020.00073. PMID: 32185142; PMCID: PMC7058978.
- Song SJ, et al. Cohabiting family members share microbiota with one another and with their dogs. Elife. 2013 Apr 16;2:e00458. doi: 10.7554/eLife.00458. PMID: 23599893; PMCID: PMC3628085.
- Valeri F, Endres K. How biological sex of the host shapes its gut microbiota. Front Neuroendocrinol. 2021 Apr;61:100912. doi: 10.1016/j.yfrne.2021.100912. Epub 2021 Mar 10. PMID: 33713673.
- Kim YS, Unno T, Kim BY, Park MS. Sex Differences in Gut Microbiota. World J Mens Health. 2020 Jan;38(1):48-60. doi: 10.5534/wjmh.190009. Epub 2019 Mar 25. PMID: 30929328; PMCID: PMC6920072.
- Jašarević E, Morrison KE, Bale TL. Sex differences in the gut microbiome-brain axis across the lifespan. Philos Trans R Soc Lond B Biol Sci. 2016 Feb 19;371(1688):20150122. doi: 10.1098/rstb.2015.0122. Epub 2016 Feb 1. PMID: 26833840; PMCID: PMC4785905.
- Yuan, X., Chen, R., Zhang, Y. et al. Sexual dimorphism of gut microbiota at different pubertal status. Microb Cell Fact 19, 152 (2020). https://doi.org/10.1186/s12934-020-01412-2
- So SY, Savidge TC. Sex-Bias in Irritable Bowel Syndrome: Linking Steroids to the Gut-Brain Axis. Front Endocrinol (Lausanne). 2021 May 19;12:684096. doi: 10.3389/fendo.2021.684096. PMID: 34093447; PMCID: PMC8170482.
- Yoon K, Kim N. Roles of Sex Hormones and Gender in the Gut Microbiota. J Neurogastroenterol Motil. 2021 Jul 30;27(3):314-325. doi: 10.5056/jnm20208. PMID: 33762473; PMCID: PMC8266488.
- de la Cuesta-Zuluaga J, Kelley ST, Chen Y, Escobar JS, Mueller NT, Ley RE, McDonald D, Huang S, Swafford AD, Knight R, Thackray VG. Age- and Sex-Dependent Patterns of Gut Microbial Diversity in Human Adults. mSystems. 2019 May 14;4(4):e00261-19. doi: 10.1128/mSystems.00261-19. PMID: 31098397; PMCID: PMC6517691.
- Vemuri R, et al. The microgenderome revealed: sex differences in bidirectional interactions between the microbiota, hormones, immunity and disease susceptibility. Semin Immunopathol. 2019 Mar;41(2):265-275. doi: 10.1007/s00281-018-0716-7. Epub 2018 Oct 8. PMID: 30298433; PMCID: PMC6500089.
- Atoum M, Padma K. Gut microbiota-estrogen axis: Its influence on female health outcomes – A narrative review. Acta Biomed. 2025;96(1):15980. doi:10.23750/abm.v96i1.15980
- Yang PL, Heitkemper MM, Kamp KJ. Irritable bowel syndrome in midlife women: a narrative review. Womens Midlife Health. 2021 May 31;7(1):4. doi: 10.1186/s40695-021-00064-5. PMID: 34059117; PMCID: PMC8166071.
- Sisk-Hackworth, L., Kelley, S. T., & Thackray, V. G. (2023). Sex, puberty, and the gut microbiome. Reproduction, 165(2), R61–R74. https://doi.org/10.1530/REP-22-0303
- Yao Y, Hu H, Chen L, Zheng H. Association between gut microbiota and menstrual disorders: a two-sample Mendelian randomization study. Front Microbiol. 2024 Mar 7;15:1321268. doi: 10.3389/fmicb.2024.1321268. PMID: 38516009; PMCID: PMC10954809.
- Peters BA, Santoro N, Kaplan RC, Qi Q. Spotlight on the Gut Microbiome in Menopause: Current Insights. Int J Womens Health. 2022 Aug 10;14:1059-1072. doi: 10.2147/IJWH.S340491. PMID: 35983178; PMCID: PMC9379122.
- Nannini, G.; Cei, F.; Amedei, A. Unraveling the Contribution of Estrobolome Alterations to Endometriosis Pathogenesis. Curr. Issues Mol. Biol. 2025, 47, 502. https://doi.org/10.3390/cimb47070502
- Moreno I, Simon C. Deciphering the effect of reproductive tract microbiota on human reproduction. Reprod Med Biol. 2018 Nov 1;18(1):40-50. doi: 10.1002/rmb2.12249. PMID: 30655720; PMCID: PMC6332752.
- Siddiqui, R. et al. The gut microbiome and female health. Biology, 2022.11(11), 1683. https://doi.org/10.3390/biology11111683
- Park SL, Kim MS, Kim TH. Gut Microbiome and Estrogen. J Menopausal Med. 2025 Aug;31(2):95-101. doi: 10.6118/jmm.24024. PMID: 40954993; PMCID: PMC12438150.
- Chidi-Ogbolu N, Baar Effect of Estrogen on Musculoskeletal Performance and Injury Risk. Front Physiol. 2019 Jan 15;9:1834. doi: 10.3389/fphys.2018.01834. PMID: 30697162; PMCID: PMC6341375.
- Schoep ME, et al. The impact of menstrual symptoms on everyday life: a survey among 42,879 women. Am J Obstet Gynecol. 2019 Jun;220(6):569.e1-569.e7. doi: 10.1016/j.ajog.2019.02.048. Epub 2019 Mar 15. PMID: 30885768.
- Hantsoo, L. et al. Premenstrual symptoms across the lifespan in an international sample: data from a mobile application. Archives of Women’s Mental Health, 2022, 25(5), 903–910. https://doi.org/10.1007/s00737-022-01261
- Pati GK, et al. Irritable Bowel Syndrome and the Menstrual Cycle. Cureus. 2021 Jan 14;13(1):e12692. doi: 10.7759/cureus.12692. PMID: 33614302; PMCID: PMC7883586.
- Heitkemper MM, Chang L. Do fluctuations in ovarian hormones affect gastrointestinal symptoms in women with irritable bowel syndrome? Gend Med. 2009;6 Suppl 2(Suppl 2):152-67. doi: 10.1016/j.genm.2009.03.004. PMID: 19406367; PMCID: PMC3322543.
- Bharadwaj S, et al. Symptomatology of irritable bowel syndrome and inflammatory bowel disease during the menstrual cycle. Gastroenterol Rep (Oxf). 2015 Aug;3(3):185-93. doi: 10.1093/gastro/gov010. Epub 2015 Mar 18. PMID: 25788484; PMCID: PMC4527267.
- Takeda T, et al. K. Characteristics of the gut microbiota in women with premenstrual symptoms: A cross-sectional study. PLoS One. 2022 May 27;17(5):e0268466. doi: 10.1371/journal.pone.0268466. PMID: 35622782; PMCID: PMC9140228.
- Baker JM, Al-Nakkash L, Herbst-Kralovetz MM. Estrogen-gut microbiome axis: Physiological and clinical implications. Maturitas. 2017 Sep;103:45-53. doi: 10.1016/j.maturitas.2017.06.025. Epub 2017 Jun 23. PMID: 28778332.
- Ervin, S. M. et al. Gut microbial β-glucuronidases reactivate estrogens as components of the estrobolome. Journal of Biological Chemistry, 2019, 294(49), 18586–18599. https://doi.org/10.1074/jbc.RA119.010950
- Li VW, et al. Mass spectrometric profiling of primary estrogens and estrogen metabolites in human stool and plasma partially elucidates the role of the gut microbiome in estrogen recycling. Mol Cell Endocrinol. 2025 Jun 1;603:112534. doi: 10.1016/j.mce.2025.112534. Epub 2025 Apr 1. PMID: 40180172.
- Leeners B, Geary N, Tobler PN, Asarian L. Ovarian hormones and obesity. Hum Reprod Update. 2017 May 1;23(3):300-321. doi: 10.1093/humupd/dmw045. PMID: 28333235; PMCID: PMC5850121.
- Cappelletti M, Wallen K. Increasing women’s sexual desire: The comparative effectiveness of estrogens and androgens. Horm Behav. 2016 Feb;78:178-93. doi: 10.1016/j.yhbeh.2015.11.003. Epub 2015 Nov 14. PMID: 26589379; PMCID: PMC4720522.
- Payne JL. The role of estrogen in mood disorders in women. Int Rev Psychiatry. 2003 Aug;15(3):280-90. doi: 10.1080/0954026031000136893. PMID: 15276966.
- Emmanuelle NE, Marie-Cécile V, Florence T, Jean-François A, Françoise L, Coralie F, Alexia V. Critical Role of Estrogens on Bone Homeostasis in Both Male and Female: From Physiology to Medical Implications. Int J Mol Sci. 2021 Feb 4;22(4):1568. doi: 10.3390/ijms22041568. PMID: 33557249; PMCID: PMC7913980.
- Craig MC, Murphy DG. Estrogen: effects on normal brain function and neuropsychiatric disorders. Climacteric. 2007 Oct;10 Suppl 2:97-104. doi: 10.1080/13697130701598746. PMID: 17882683.
- Chakraborty B, Byemerwa J, Krebs T, Lim F, Chang CY, McDonnell DP. Estrogen Receptor Signaling in the Immune System. Endocr Rev. 2023 Jan 12;44(1):117-141. doi: 10.1210/endrev/bnac017. PMID: 35709009.
- Aryan L, Younessi D, Zargari M, Banerjee S, Agopian J, Rahman S, Borna R, Ruffenach G, Umar S, Eghbali M. The Role of Estrogen Receptors in Cardiovascular Disease. Int J Mol Sci. 2020 Jun 17;21(12):4314. doi: 10.3390/ijms21124314. PMID: 32560398; PMCID: PMC7352426.
- Judkins TC, Dennis-Wall JC, Sims SM, Colee J, Langkamp-Henken B. Stool frequency and form and gastrointestinal symptoms differ by day of the menstrual cycle in healthy adult women taking oral contraceptives: a prospective observational study. BMC Womens Health. 2020 Jun 29;20(1):136. doi: 10.1186/s12905-020-01000-x. PMID: 32600463; PMCID: PMC7325082.
- Rogan MM, Black KE. Dietary energy intake across the menstrual cycle: a narrative review. Nutr Rev. 2023 Jun 9;81(7):869-886. doi: 10.1093/nutrit/nuac094. PMID: 36367830; PMCID: PMC10251302.
- Brott, N. R., & Le, J. K. Mittelschmerz, 2025, Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
- Mulak A, Taché Y, Larauche M. Sex hormones in the modulation of irritable bowel syndrome. World J Gastroenterol. 2014 Mar 14;20(10):2433-48. doi: 10.3748/wjg.v20.i10.2433. PMID: 24627581; PMCID: PMC3949254.
- Jung HK, Kim DY, Moon IH. Effects of gender and menstrual cycle on colonic transit time in healthy subjects. Korean J Intern Med. 2003 Sep;18(3):181-6. doi: 10.3904/kjim.2003.18.3.181. PMID: 14619388; PMCID: PMC4531623.
- Brown, D. et al. The experiences and psychological impact of living with premenstrual disorders: A systematic review and thematic synthesis. Frontiers in Psychiatry, 2024 15, 1440690. . https://doi.org/10.3389/fpsyt.2024.1440690
- Heller C, et al. Why menstrual cycle irregularities belong in brain research. Nat Med. 2025 Aug 13. doi: 10.1038/s41591-025-03879-1. Epub ahead of print. PMID: 40804324.
- Broughton T, et al. Increased risk of provisional premenstrual dysphoric disorder (PMDD) among females with attention-deficit hyperactivity disorder (ADHD): cross-sectional survey study. Br J Psychiatry. 2025 Jun;226(6):410-417. doi: 10.1192/bjp.2025.104. Epub 2025 Jun 18. PMID: 40528384; PMCID: PMC7617793.
- Khalil, Jacqueline MS, et al. rmone Replacement Therapy is Associated With Increased Risk of Developing Irritable Bowel Syndrome in Post-Menopausal Women. The American Journal of Gastroenterology 119(10S):p S547, October 2024. | DOI: 10.14309/01.ajg.0001032540.54524.37
- Houghton LA, Lea R, Jackson N, Whorwell PJ. The menstrual cycle affects rectal sensitivity in patients with irritable bowel syndrome but not healthy volunteers. 2002 Apr;50(4):471-4. doi: 10.1136/gut.50.4.471. PMID: 11889064; PMCID: PMC1773170.
- Altman G, et al. Increased symptoms in female IBS patients with dysmenorrhea and PMS. Gastroenterol Nurs. 2006 Jan-Feb;29(1):4-11. doi: 10.1097/00001610-200601000-00002. PMID: 16552294.
- The Study of Women’s Health Across the Nation (SWAN) https://www.swanstudy.org/
- DiVasta AD, et al. Overlap Between Irritable Bowel Syndrome Diagnosis and Endometriosis in Adolescents. Clin Gastroenterol Hepatol. 2021 Mar;19(3):528-537.e1. doi: 10.1016/j.cgh.2020.03.014. Epub 2020 Mar 14. PMID: 32184183.
- Maroun P, et al. Relevance of gastrointestinal symptoms in endometriosis. Aust N Z J Obstet Gynaecol. 2009 Aug;49(4):411-4. doi: 10.1111/j.1479-828X.2009.01030.x. PMID: 19694698.
https://www.endometriose.nl/ - https://endometriosewijzer.nl/
- WHO Newsroom World Health Organization (WHO) (2023) Endometriosis.
https://www.who.int/news-room/fact-sheets/detail/endometriosis
- V. Wijbers et al. Invloed van dieetinterventies bij de behandeling van endometriose, (NED TIJDSCHR LEEFSTIJLGENEESKD 2024;2(5):196–201)
- Uzuner C, et al The bidirectional relationship between endometriosis and microbiome. Front Endocrinol (Lausanne). 2023 Mar 7;14:1110824. doi: 10.3389/fendo.2023.1110824. PMID: 36960395; PMCID: PMC10028178.
- Salliss ME, et al. The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain. Hum Reprod Update. 2021 Dec 21;28(1):92-131. doi: 10.1093/humupd/dmab035. PMID: 34718567.
- Jiang I, Yong PJ, Allaire C, Bedaiwy MA. Intricate Connections between the Microbiota and Endometriosis. Int J Mol Sci. 2021 May 26;22(11):5644. doi: 10.3390/ijms22115644. PMID: 34073257; PMCID: PMC8198999.
- García-Peñarrubia P. et al Hypothetical roadmap towards endometriosis: prenatal endocrine-disrupting chemical pollutant exposure, anogenital distance, gut-genital microbiota and subclinical infections. Hum Reprod Update. 2020 Feb 28;26(2):214-246. doi: 10.1093/humupd/dmz044. PMID: 32108227.
- Qi, X., Yun, C., Pang, Y., & Qiao, J. (2021). The impact of the gut microbiota on the reproductive and metabolic endocrine system. Gut Microbes, 13(1). https://doi.org/10.1080/19490976.2021.1894070
- Martire FG. Et al. Endometriosis and Nutrition: Therapeutic Perspectives. J Clin Med. 2025 Jun 5;14(11):3987. doi: 10.3390/jcm14113987. PMID: 40507748; PMCID: PMC12156139.
- Nabi MY, Nauhria S, Reel M, Londono S, Vasireddi A, Elmiry M, Ramdass PVAK. Endometriosis and irritable bowel syndrome: A systematic review and meta-analyses. Front Med (Lausanne). 2022 Jul 25;9:914356. doi: 10.3389/fmed.2022.914356. PMID: 35957857; PMCID: PMC9357916.
- Viganò D, Zara F, Usai P. Irritable bowel syndrome and endometriosis: New insights for old diseases. Dig Liver Dis. 2018 Mar;50(3):213-219. doi: 10.1016/j.dld.2017.12.017. Epub 2017 Dec 27. PMID: 29396128
Li J, Jia Y, Xu H, Bing H, Ling Q, Wang S, Wang Y, Zhang X, Zhao L. Exploring the interactions of gut microbiome and metabolites in polycystic ovary syndrome: a review. Microbiol Res. 2025 Dec;301:128309. doi: 10.1016/j.micres.2025.128309. Epub 2025 Aug 12. PMID: 40829509. - Calcaterra V. et al Probiotics and Polycystic Ovary Syndrome: A Perspective for Management in Adolescents with Obesity. Nutrients. 2023 Jul 14;15(14):3144. doi: 10.3390/nu15143144. PMID: 37513562; PMCID: PMC10384396.
- Li C, Cheng D, Ren H, Zhang T. Unraveling the gut microbiota’s role in PCOS: a new frontier in metabolic health. Front Endocrinol (Lausanne). 2025 Mar 18;16:1529703. doi: 10.3389/fendo.2025.1529703. PMID: 40171188; PMCID: PMC11958223.
- Jobira B. et al. Obese Adolescents With PCOS Have Altered Biodiversity and Relative Abundance in Gastrointestinal Microbiota. J Clin Endocrinol Metab. 2020 Jun 1;105(6):e2134–44. doi: 10.1210/clinem/dgz263. PMID: 31970418; PMCID: PMC7147870.
- Calcaterra V, Verduci E, Cena H, Magenes VC, Todisco CF, Tenuta E, Gregorio C, De Giuseppe R, Bosetti A, Di Profio E, Zuccotti G. Polycystic Ovary Syndrome in Insulin-Resistant Adolescents with Obesity: The Role of Nutrition Therapy and Food Supplements as a Strategy to Protect Fertility. Nutrients. 2021 May 28;13(6):1848. doi: 10.3390/nu13061848. PMID: 34071499; PMCID: PMC8228678.
- Colldén H. et al. The gut microbiota is a major regulator of androgen metabolism in intestinal contents. Am J Physiol Endocrinol Metab. 2019 Dec 1;317(6):E1182-E1192. doi: 10.1152/ajpendo.00338.2019. Epub 2019 Nov 5. PMID: 31689143; PMCID: PMC6962501.
- Torres PJ, et al. Gut Microbial Diversity in Women With Polycystic Ovary Syndrome Correlates With Hyperandrogenism. J Clin Endocrinol Metab. 2018 Apr 1;103(4):1502-1511. doi: 10.1210/jc.2017-02153. PMID: 29370410; PMCID: PMC6276580.
- Guo J, et al. Gut Microbiota in Patients with Polycystic Ovary Syndrome: a Systematic Review. Reprod Sci. 2022 Jan;29(1):69-83. doi: 10.1007/s43032-020-00430-0. Epub 2021 Jan 6. PMID: 33409871.
- Lindheim L. et al. Alterations in Gut Microbiome Composition and Barrier Function Are Associated with Reproductive and Metabolic Defects in Women with Polycystic Ovary Syndrome (PCOS): A Pilot Study. PLoS One. 2017 Jan 3;12(1):e0168390. doi: 10.1371/journal.pone.0168390. PMID: 28045919; PMCID: PMC5207627.
- Helena J Teede, Chau Thien Tay, Joop J E Laven, Anuja Dokras, Lisa J Moran, Terhi T Piltonen, Michael F Costello, Jacky Boivin, Leanne M Redman, Jacqueline A Boyle, Robert J Norman, Aya Mousa, Anju E Joham, the International PCOS Network , Recommendations from the 2023 international evidence-based guideline for the assessment and management of polycystic ovary syndrome, European Journal of Endocrinology, Volume 189, Issue 2, August 2023, Pages G43–G64, https://doi.org/10.1093/ejendo/lvad096
- Li Y, Tan Y, Xia G, Shuai J. Effects of probiotics, prebiotics, and synbiotics on polycystic ovary syndrome: a systematic review and meta-analysis. Crit Rev Food Sci Nutr. 2023;63(4):522-538. doi: 10.1080/10408398.2021.1951155. Epub 2021 Jul 21. PMID: 34287081.
- Angoorani P, et al. The effects of probiotics, prebiotics, and synbiotics on polycystic ovarian syndrome: an overview of systematic reviews. Front Med (Lausanne). 2023 Jun 9;10:1141355. doi: 10.3389/fmed.2023.1141355. PMID: 37359018; PMCID: PMC10288857.
- Cozzolino M, et al. Therapy with probiotics and synbiotics for polycystic ovarian syndrome: a systematic review and meta-analysis. Eur J Nutr. 2020 Oct;59(7):2841-2856. doi: 10.1007/s00394-020-02233-0. Epub 2020 May 5. Erratum in: Eur J Nutr. 2022 Jun;61(4):2233-2235. doi: 10.1007/s00394-022-02856-5. PMID: 32372265.
- Davis SR, Lambrinoudaki I, Lumsden M, Mishra GD, Pal L, Rees M, Santoro N, Simoncini T. Menopause. Nat Rev Dis Primers. 2015 Apr 23;1:15004. doi: 10.1038/nrdp.2015.4. PMID: 27188659.
- Oude Hengel, K, et al. De overgang: klachten en de invloed op het werk. Verdiepend onderzoek van de Nationale Enquête Arbeidsomstandigheden (NEA), TNO-rapport, Projectnummer 060.47155/01.19. Rapportnummer TNO 2022 R10823
- Lin F, Ma L, Sheng Z. Health disorders in menopausal women: microbiome alterations, associated problems, and possible treatments. Biomed Eng Online. 2025 Jul 7;24(1):84. doi: 10.1186/s12938-025-01415-3. PMID: 40624665; PMCID: PMC12235801.
- Wang H, Shi F, Zheng L, Zhou W, Mi B, Wu S, Feng X. Gut microbiota has the potential to improve health of menopausal women by regulating estrogen. Front Endocrinol (Lausanne). 2025 Jun 9;16:1562332. doi: 10.3389/fendo.2025.1562332. PMID: 40551890; PMCID: PMC12183514.
- Peters BA. Et al. Menopause Is Associated with an Altered Gut Microbiome and Estrobolome, with Implications for Adverse Cardiometabolic Risk in the Hispanic Community Health Study/Study of Latinos. mSystems. 2022 Jun 28;7(3):e0027322. doi: 10.1128/msystems.00273-22. Epub 2022 Apr 13. PMID: 35675542; PMCID: PMC9239235.
- Mayneris-Perxachs J, et al. Gut microbiota steroid sexual dimorphism and its impact on gonadal steroids: influences of obesity and menopausal status. Microbiome. 2020 Sep 20;8(1):136. doi: 10.1186/s40168-020-00913-x. PMID: 32951609; PMCID: PMC7504665.
- Santos-Marcos JA, et al. Influence of gender and menopausal status on gut microbiota. Maturitas. 2018 Oct;116:43-53. doi: 10.1016/j.maturitas.2018.07.008. Epub 2018 Jul 19. Erratum in: Maturitas. 2025 Aug;199:108641. doi: 10.1016/j.maturitas.2025.108641. PMID: 30244778.
- Barth C, Villringer A, Sacher J. Sex hormones affect neurotransmitters and shape the adult female brain during hormonal transition periods. Front Neurosci. 2015 Feb 20;9:37. doi: 10.3389/fnins.2015.00037. PMID: 25750611; PMCID: PMC4335177.
- McEwen BS, Milner TA. Understanding the broad influence of sex hormones and sex differences in the brain. J Neurosci Res. 2017 Jan 2;95(1-2):24-39. doi: 10.1002/jnr.23809. PMID: 27870427; PMCID: PMC5120618.
- Zárate S, Stevnsner T, Gredilla R. Role of Estrogen and Other Sex Hormones in Brain Aging. Neuroprotection and DNA Repair. Front Aging Neurosci. 2017 Dec 22;9:430. doi: 10.3389/fnagi.2017.00430. PMID: 29311911; PMCID: PMC5743731.
- Hill, C. et al. The International Scientific Association for Probiotics and Prebiotics Consensus Statement on the scope and appropriate use of the term Probiotic. Nature Reviews Gastroenterology & Hepatology, 2014. 11(8), 506–514.
- Chen MS, et al. The association between dietary fiber and infertility among US Women: The National Health and Nutrition Examination Survey, 2013-2018. Nutr Hosp. 2022 Dec 20;39(6):1333-1340. English. doi: 10.20960/nh.04056. PMID: 36373676.
- Zidan S, et al. Could psychobiotics and fermented foods improve mood in middle-aged and older women? Maturitas. 2024 Mar;181:107903. doi: 10.1016/j.maturitas.2023.107903. Epub 2023 Dec 21. PMID: 38157685.
- Stachenfeld NS, et al. Water intake reverses dehydration associated impaired executive function in healthy young women. Physiol Behav. 2018 Mar 1;185:103-111. doi: 10.1016/j.physbeh.2017.12.028. Epub 2017 Dec 23. PMID: 29277553.
- Armstrong LE, et al. Mild dehydration affects mood in healthy young women. J Nutr. 2012 Feb;142(2):382-8. doi: 10.3945/jn.111.142000. Epub 2011 Dec 21. PMID: 22190027.
- Engen PA, et al. The Gastrointestinal Microbiome: Alcohol Effects on the Composition of Intestinal Microbiota. Alcohol Res. 2015;37(2):223-36. PMID: 26695747; PMCID: PMC4590619.
- Jun S, et al. Cancer risk based on alcohol consumption levels: a comprehensive systematic review and meta-analysis. Epidemiol Health. 2023;45:e2023092. doi: 10.4178/epih.e2023092. Epub 2023 Oct 16. PMID: 37905315; PMCID: PMC10867516.
- World Health Organization (WHO). (2020). WHO guideline on use of ferritin concentrations to assess iron status in individuals and populations. Geneva: World Health Organization.
- Munro MG, et al. The relationship between heavy menstrual bleeding, iron deficiency, and iron deficiency anemia. Am J Obstet Gynecol. 2023 Jul;229(1):1-9. doi: 10.1016/j.ajog.2023.01.017. Epub 2023 Jan 24. PMID: 36706856.
- Menni, C., Zierer, J., Pallister, T. et al.Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women. Sci Rep 7, 11079 (2017). https://doi.org/10.1038/s41598-017-10382-2
- Koçak, M., Şevgin, Ö. The effect of exercise on menstrual symptoms: a randomized controlled trial. BMC Women’s Health25, 406 (2025). https://doi.org/10.1186/s12905-025-03940-8
- Varghese S, et al. Physical Exercise and the Gut Microbiome: A Bidirectional Relationship Influencing Health and Performance. 2024 Oct 28;16(21):3663. doi: 10.3390/nu16213663. PMID: 39519496; PMCID: PMC11547208.
- Rostami-Moez, M., Shobeiri, F., Otogara, M., et al. (2023). Examining the Health-Related Needs of Females During Menopause: A Systematic Review study. Journal of Menopausal Medicine, 29(1), 1.
- Pluchino, N., Bucci, F., Cela, V., et al. (2011). Menopause and Mental Well-Being: Timing of symptoms and Timing of hormone treatment. Women’s Health, 7(1), 71–80.
- https://www.voedingscentrum.nl/encyclopedie/ijzer.aspx
- Mohammadi MM, Mirjalili R, Faraji A. The impact of omega-3 polyunsaturated fatty acids on primary dysmenorrhea: a systematic review and meta-analysis of randomized controlled trials. Eur J Clin Pharmacol. 2022 May;78(5):721-731. doi: 10.1007/s00228-021-03263-1. Epub 2022 Jan 21. PMID: 35059756.
- Najafi N, Khalkhali H, Moghaddam Tabrizi F, Zarrin R. Major dietary patterns in relation to menstrual pain: a nested case control study. BMC Womens Health. 2018 May 21;18(1):69. doi: 10.1186/s12905-018-0558-4. PMID: 29783972; PMCID: PMC5963185.
- Leeuwendaal NK, Stanton C, O’Toole PW, Beresford TP. Fermented Foods, Health and the Gut Microbiome. Nutrients. 2022 Apr 6;14(7):1527. doi: 10.3390/nu14071527. PMID: 35406140; PMCID: PMC9003261.
- López-Liria R, et al. Efficacy of Physiotherapy Treatment in Primary Dysmenorrhea: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2021 Jul 23;18(15):7832. doi: 10.3390/ijerph18157832. PMID: 34360122; PMCID: PMC8345570.
- Jeon B, Baek J. Menstrual disturbances and its association with sleep disturbances: a systematic review. BMC Womens Health. 2023 Sep 1;23(1):470. doi: 10.1186/s12905-023-02629-0. PMID: 37658359; PMCID: PMC10474748.
- Yeung EH, et al. Longitudinal study of insulin resistance and sex hormones over the menstrual cycle: the BioCycle Study. J Clin Endocrinol Metab. 2010 Dec;95(12):5435-42. doi: 10.1210/jc.2010-0702. Epub 2010 Sep 15. PMID: 20843950; PMCID: PMC2999972.
- Viswanathan M, et al. Folic Acid Supplementation to Prevent Neural Tube Defects: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2023 Aug 1;330(5):460-466. doi: 10.1001/jama.2023.9864. PMID: 37526714.
- Tokarczyk J, Koch W. Dietary Zn—Recent Advances in Studies on Its Bioaccessibility and Bioavailability. Molecules. 2025; 30(13):2742. https://doi.org/10.3390/molecules30132742
- Milanković V, et al. Metals on the Menu—Analyzing the Presence, Importance, and Consequences. Foods. 2024; 13(12):1890. https://doi.org/10.3390/foods13121890
- Hromatko I, Mikac U. A Mid-Cycle Rise in Positive and Drop in Negative Moods among Healthy Young Women: A Pilot Study. Brain Sci. 2023 Jan 5;13(1):105. doi: 10.3390/brainsci13010105. PMID: 36672085; PMCID: PMC9856962.
- Chavarro JE, Rich-Edwards JW, Rosner BA, Willett WC. A prospective study of dietary carbohydrate quantity and quality in relation to risk of ovulatory infertility. Eur J Clin Nutr. 2009 Jan;63(1):78-86. doi: 10.1038/sj.ejcn.1602904. Epub 2007 Sep 19. PMID: 17882137; PMCID: PMC3066074.
- Jukic AMZ, Wilcox AJ, McConnaughey DR, Weinberg CR, Steiner AZ. 25-Hydroxyvitamin D and Long Menstrual Cycles in a Prospective Cohort Study. Epidemiology. 2018 May;29(3):388-396. doi: 10.1097/EDE.0000000000000804. PMID: 29337846; PMCID: PMC5882585.
- Tucker JAL, et al. The Effect of the Menstrual Cycle on Energy Intake: A Systematic Review and Meta-analysis. Nutr Rev. 2025 Mar 1;83(3):e866-e876. doi: 10.1093/nutrit/nuae093. PMID: 39008822; PMCID: PMC11819481.
- Gorczyca AM, et al. Changes in macronutrient, micronutrient, and food group intakes throughout the menstrual cycle in healthy, premenopausal women. Eur J Nutr. 2016 Apr;55(3):1181-8. doi: 10.1007/s00394-015-0931-0. Epub 2015 Jun 5. PMID: 26043860; PMCID: PMC6257992.
- Robinson J, et al. Effect of nutritional interventions on the psychological symptoms of premenstrual syndrome in women of reproductive age: a systematic review of randomized controlled trials. Nutr Rev. 2025 Feb 1;83(2):280-306. doi: 10.1093/nutrit/nuae043. PMID: 38684926; PMCID: PMC11723155.
- Abdi F, Ozgoli G, Rahnemaie FS. A systematic review of the role of vitamin D and calcium in premenstrual syndrome. Obstet Gynecol Sci. 2019 Mar;62(2):73-86. doi: 10.5468/ogs.2019.62.2.73. Epub 2019 Feb 25. Erratum in: Obstet Gynecol Sci. 2020 Mar;63(2):213. doi: 10.5468/ogs.2020.63.2.213. PMID: 30918875; PMCID: PMC6422848.
- Rael B, et al. Menstrual Cycle Phases Influence on Cardiorespiratory Response to Exercise in Endurance-Trained Females. Int J Environ Res Public Health. 2021 Jan 20;18(3):860. doi: 10.3390/ijerph18030860. PMID: 33498274; PMCID: PMC7908534.
- Alzueta E, Baker FC. The Menstrual Cycle and Sleep. Sleep Med Clin. 2023 Dec;18(4):399-413. doi: 10.1016/j.jsmc.2023.06.003. Epub 2023 Jul 16. PMID: 38501513; PMCID: PMC11562818.
- Sato A, Fukawa-Nagira A, Sashihara T. Lactobacillus paragasseriOLL2809 Improves Premenstrual Psychological Symptoms in Healthy Women: A Randomized, Double-Blind, Placebo-Controlled Study. Nutrients. 2023 Dec 1;15(23):4985. doi: 10.3390/nu15234985. PMID: 38068843; PMCID: PMC10707835.
